The most recent crash of a Boeing 737 was on January 8, 2020, when Ukraine International Airlines Flight 752 crashed after takeoff from Tehran Imam Khomeini International Airport.

Here is a list of several accidents involving the Boeing 737 that were fatal.

The first fatal accident for a 737 was in December 8, 1972. United Airlines Flight 553, a 737-200 registration N9031U, crashed while attempting to land at Chicago Midway International Airport. Two people on the ground and 43 of the 61 passengers and crew on board were killed.

May 31, 1973 – Indian Airlines Flight 440, a 737-200, crashed while on approach to Palam International Airport in New Delhi, India. Of the 65 passengers and crew on board, 48 were killed.

February 11, 1978 – Pacific Western Airlines Flight 314, a 737-200, crashed while attempting to land at Cranbrook Airport, British Columbia, Canada. The aircraft crashed after thrust reversers did not fully stow following a go-around that was executed in order to avoid a snowplough. The crash killed four of the crew members and 38 of the 44 passengers.

July 11, 1983 – TAME 737-2V2 Advanced, registration HC-BIG, crashed while attempting to land at Mariscal Lamar Airport, killing all 111 passengers and eight crew on board. The cause of the crash was a CFIT (Controlled Flight Into Terrain) as a result of the pilot's inexperience with the aircraft. It remains the deadliest aviation accident in Ecuadorean history.[24][25][26] after a radio station reported witnesses to a mid-air explosion.

August 22, 1985 – British Airtours Flight 28M, a 737-200, aborted its takeoff at Manchester Airport, UK, after it caught fire due to a crack in one of the combustors of the left Pratt & Whitney JT8D-15 engine. Of the 136 passengers and crew on board, 56 died, most due to toxic smoke inhalation. Research following the accident investigation led to many innovations in air safety, including a redesign of the 737's galley area.

Aloha Airlines Flight 243 after its emergency landing at Kahului, Maui in April 1988

April 28, 1988 – Aloha Airlines Flight 243, a 737-200, suffered extensive damage after an explosive decompression at an altitude of 24,000 feet (7,300 m), but was able to land safely at Kahului Airport on the island of Maui with one fatality. A flight attendant, Clarabelle (C.B.) Lansing, who was not in restraints at the moment of decompression, was blown out of the aircraft over the ocean and her body was never found.

September 29, 2006:

Gol Transportes Aéreos Flight 1907, a brand-new 737-800 with 154 people on board broke up and crashed following a mid-air collision in Brazil with an Embraer Legacy 600. All onboard the 737-800 were killed. The Legacy landed safely at a Brazilian Air Force base.

May 5, 2007:

Kenya Airways Flight 507, a 737-800 carrying 105 passengers and nine crew lost contact and crashed into a swamp on a flight to Nairobi, Kenya from Abidjan, Côte d'Ivoire, after making a scheduled stop at Douala, Cameroon. There were no survivors.

February 25, 2009:

Turkish Airlines Flight 1951, a 737-800 coming from Istanbul, crashed in a field near the Polderbaan while attempting to land at Amsterdam's Schiphol Airport. The fuselage broke into three pieces after the crash and the engine pylons separated. Of the 135 passengers and crew, there were nine fatalities: five passengers and four crew members (including both pilots and a pilot-in-training); 84 people suffered injuries. Crash investigations initially focused on a malfunctioning left radar altimeter, which may have resulted in false altitude information causing the autothrottle to reduce power.

January 25, 2010:

Ethiopian Airlines Flight 409, a 737-800, crashed into the Mediterranean Sea shortly after take-off from Beirut Rafic Hariri International Airport. The flight had 90 passengers and 8 crew, 50 passengers of whom were Lebanese, and was bound for the Ethiopian capital of Addis Ababa. There were no survivors.

March 19, 2016:

Flydubai Flight 981, a 737-800 flying from Dubai, United Arab Emirates to Rostov-on-Don, Russia, crashed on the final approach to Rostov-on-Don Airport in inclement weather. All 62 people on board died.

October 29, 2018:

Lion Air Flight 610, a 737 MAX 8, registration PK-LQP, on a flight from Jakarta, Indonesia to Pangkal Pinang, Indonesia, crashed into the sea 13 minutes after takeoff, with 189 people on board the aircraft: 181 passengers (178 adults and three children), as well as six cabin crew and two pilots. The crash killed all aboard. This is the deadliest air accident involving all variants of the Boeing 737 and also the first accident involving the Boeing 737 MAX.

March 10, 2019:

Ethiopian Airlines Flight 302, a 737 MAX 8, registration ET-AVJ, on a flight from Addis Ababa, Ethiopia to Nairobi, Kenya, crashed 6 minutes after takeoff, killing all 157 people aboard: 149 passengers and 8 crew members. The plane was only 4 months old at the time of the accident. In response, numerous aviation authorities around the world grounded the 737 MAX, and many airlines followed suit on a voluntary basis. On March 13, 2019, the FAA became the last authority to ground the aircraft, reversing its previous stance that the MAX was safe to fly.