He died at home in Los Angeles with his wife and family by his side, a statement posted on social media said.
Boseman was diagnosed with colon cancer four years before his death but had not made the information public.
While marking his 2nd death anniversary in August, Lupita said filming season 2 of Wakanda was challenging but powerful.
"It was very therapeutic. It restored a sense of hope for me in making it, and I think we’ve expanded the world of Wakanda in ways that will blow people’s minds — not just Wakanda, but the Black Panther world. It’s going to blow people’s minds, and I just cannot wait until it’s not a secret anymore."
Check out tribute messages from Lupita's fans;
mina_bkallday: I feel like this man is in my family 🥺 so missed.
kailyndavillier: You two smiling is the highlight of my day! Thank you for sharing this with us.
aplbrilliance: And just to think he was sick during all of this is just so heartbreaking now to watch him smiling and laughing, while knowing we all don't know we're about to lose him😢 Bless his beautiful soul. He's our Black Panther forever.
americanthaiguy: I didn't know him personally but he made an impact on me. I'm still devastated and miss his presence. We need more people like him in this world. 💔 Rest in peace, cousin.
Read Also
How Pikika Brunch Fest went down at Arboretum Gardens